Quantum major static/crackles Win10

Having major sound quality issues with the new Quantum.  Windows system sounds are crackling/popping on playback with zero other software running and near zero CPU load.  Youtube playback is initially crystal clear then after 20 seconds gets major crackles/pops.  Same behavior over mains and headphone output.  Took buffer to 2048, no change.  Changed process priority for TB and UC to High and Realtime, no change.

Coming from a Scarlet 6i6 2nd Gen USB which ran with no issues on the same system.  DPC latencymon is amazing (all green, no issues) and was running great via USB. I needed more I/O hence the upgrade to Quantum. 

New install of Quantum TB interface.  Updated Win10, TB firmware, TB drivers, and latest Presonus Quantum software/drivers.  Nothing else has been installed on the computer software-wise other than Ableton 10.  Strictly audio PC usage.  Not sure if its the Lenovo TB implementation, the Quantum hardware, my Startech adapter, or some other config.  I running about as pure Win10 install as one can get.

Lenovo P52
Windows 10
Thunderbolt v17.4.78.21
Startech Adapter TBT3TBTADAP