Why when I coect my AudioBox USB to my computer appears an interference?

Well, I bought the Presonus Audiobox Usb Interface recently to record my own music. Yesterday, I coected the interface to the computer by the usb port (obiously). Before clicking in Studio One 3 the window that says: (New Song), I coected my guitar and my microphone and chose the option that was in the left side of the main menu that showed a few windows with different audio ports (computer audio..) and I clicked the one which showed the "Audiobox USB". After that, I selected the window of a new song. When I only entered the recording menu of studio one 3 an interference (I think it is because it was a loud noise) showed up. Please, can someone answer me how I can fix this or what I can do?

Thank you.