Why is my program repeatedly losing files/missing files?

I use Studio One 3 Professional on a Microsoft Hp Split x2. For the 4th or 5th time in a year and a half my files have gone missing. All my work disappears and I've been able to retrieve it but I get very frustrated with the process. Why does this happen time and time again? Is it something I am doing wrong or is it a program issue? If it is a program issue I will be looking to switch programs because of this. If this is my fault I would like to understand how to prevent this from happening. There is nothing I can think of that I do to make this happen. I save all my projects, close out the program and come back to it and everything is gone.